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CDK6-ANKIB1 Fusion FISH Probe

The CDK6-ANKIB1 Fusion FISH Probe is used to confirm a fusion of the CDK6 and ANKIB1 genes. The fusion of the CDK6 and ANKIB1 genes has been associated with Pancreatic Adenocarcinoma, and Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CDK6-ANKIB1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CDK6-ANKIB1-20-RERE 20 (40 μL) 200 μL
CDK6-ANKIB1-20-REOR 20 (40 μL) 200 μL
CDK6-ANKIB1-20-REGO 20 (40 μL) 200 μL
CDK6-ANKIB1-20-REGR 20 (40 μL) 200 μL
CDK6-ANKIB1-20-REAQ 20 (40 μL) 200 μL
CDK6-ANKIB1-20-ORRE 20 (40 μL) 200 μL
CDK6-ANKIB1-20-OROR 20 (40 μL) 200 μL
CDK6-ANKIB1-20-ORGO 20 (40 μL) 200 μL
CDK6-ANKIB1-20-ORAQ 20 (40 μL) 200 μL
CDK6-ANKIB1-20-GORE 20 (40 μL) 200 μL
CDK6-ANKIB1-20-GOOR 20 (40 μL) 200 μL
CDK6-ANKIB1-20-GOGO 20 (40 μL) 200 μL
CDK6-ANKIB1-20-GOGR 20 (40 μL) 200 μL
CDK6-ANKIB1-20-GOAQ 20 (40 μL) 200 μL
CDK6-ANKIB1-20-GRRE 20 (40 μL) 200 μL
CDK6-ANKIB1-20-GROR 20 (40 μL) 200 μL
CDK6-ANKIB1-20-GRGO 20 (40 μL) 200 μL
CDK6-ANKIB1-20-GRGR 20 (40 μL) 200 μL
CDK6-ANKIB1-20-GRAQ 20 (40 μL) 200 μL
CDK6-ANKIB1-20-AQRE 20 (40 μL) 200 μL
CDK6-ANKIB1-20-AQOR 20 (40 μL) 200 μL
CDK6-ANKIB1-20-AQGO 20 (40 μL) 200 μL
CDK6-ANKIB1-20-AQGR 20 (40 μL) 200 μL
CDK6-ANKIB1-20-AQAQ 20 (40 μL) 200 μL

CDK6 Gene Summary

The protein encoded by this gene is a member of the CMGC family of serine/threonine protein kinases. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Altered expression of this gene has been observed in multiple human cancers. A mutation in this gene resulting in reduced cell proliferation, and impaired cell motility and polarity, and has been identified in patients with primary microcephaly. [provided by RefSeq, Aug 2017]

Gene Name: Cyclin Dependent Kinase 6

Chromosome: CHR7: 92234234 -92465941

Locus: 7q21.2

ANKIB1 Gene Summary

The Ankyrin Repeat And IBR Domain Containing 1 (ANKIB1) gene is located on chr7 :91875547-92030698 at 7q21.2.

Gene Name: Ankyrin Repeat And IBR Domain Containing 1

Chromosome: CHR7: 91875547 -92030698

Locus: 7q21.2

Gene Diseases

The CDK6 ANKIB1 Fusion has been associated with the following diseases:

Disease Name
Pancreatic Adenocarcinoma
Stomach Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.