SEARCH OUR PRODUCT CATALOG

CDK7-RGS20 Fusion FISH Probe

The CDK7-RGS20 Fusion FISH Probe is used to confirm a fusion of the CDK7 and RGS20 genes. The fusion of the CDK7 and RGS20 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CDK7-RGS20-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CDK7-RGS20-20-RERE 20 (40 μL) 200 μL
CDK7-RGS20-20-REOR 20 (40 μL) 200 μL
CDK7-RGS20-20-REGO 20 (40 μL) 200 μL
CDK7-RGS20-20-REGR 20 (40 μL) 200 μL
CDK7-RGS20-20-REAQ 20 (40 μL) 200 μL
CDK7-RGS20-20-ORRE 20 (40 μL) 200 μL
CDK7-RGS20-20-OROR 20 (40 μL) 200 μL
CDK7-RGS20-20-ORGO 20 (40 μL) 200 μL
CDK7-RGS20-20-ORAQ 20 (40 μL) 200 μL
CDK7-RGS20-20-GORE 20 (40 μL) 200 μL
CDK7-RGS20-20-GOOR 20 (40 μL) 200 μL
CDK7-RGS20-20-GOGO 20 (40 μL) 200 μL
CDK7-RGS20-20-GOGR 20 (40 μL) 200 μL
CDK7-RGS20-20-GOAQ 20 (40 μL) 200 μL
CDK7-RGS20-20-GRRE 20 (40 μL) 200 μL
CDK7-RGS20-20-GROR 20 (40 μL) 200 μL
CDK7-RGS20-20-GRGO 20 (40 μL) 200 μL
CDK7-RGS20-20-GRGR 20 (40 μL) 200 μL
CDK7-RGS20-20-GRAQ 20 (40 μL) 200 μL
CDK7-RGS20-20-AQRE 20 (40 μL) 200 μL
CDK7-RGS20-20-AQOR 20 (40 μL) 200 μL
CDK7-RGS20-20-AQGO 20 (40 μL) 200 μL
CDK7-RGS20-20-AQGR 20 (40 μL) 200 μL
CDK7-RGS20-20-AQAQ 20 (40 μL) 200 μL

CDK7 Gene Summary

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008]

Gene Name: Cyclin Dependent Kinase 7

Chromosome: CHR5: 68530621 -68573257

Locus: 5q13.2

RGS20 Gene Summary

The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Gene Name: Regulator Of G Protein Signaling 20

Chromosome: CHR8: 54764367 -54871863

Locus: 8q11.23

Gene Diseases

The CDK7 RGS20 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.