CELSR2-KIAA1324 Fusion FISH Probe
The CELSR2-KIAA1324 Fusion FISH Probe is used to confirm a fusion of the CELSR2 and KIAA1324 genes. The fusion of the CELSR2 and KIAA1324 genes has been associated with Breast Invasive Carcinoma, Uterine Corpus Endometrial Carcinoma, and Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CELSR2-KIAA1324-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-RERE | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-REOR | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-REGO | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-REGR | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-REAQ | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-ORRE | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-OROR | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-ORGO | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-ORAQ | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-GORE | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-GOOR | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-GOGO | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-GOGR | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-GOAQ | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-GRRE | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-GROR | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-GRGO | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-GRGR | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-GRAQ | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-AQRE | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-AQOR | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-AQGO | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-AQGR | 20 (40 μL) | 200 μL |
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| CELSR2-KIAA1324-20-AQAQ | 20 (40 μL) | 200 μL |
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CELSR2 Gene Summary
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Cadherin EGF LAG Seven-pass G-type Receptor 2
Chromosome: CHR1: 109792640 -109818378
Locus: 1p13.3
KIAA1324 Gene Summary
Expression of this gene is induced by estrogen and the encoded protein has been characterized as a transmembrane protein. The encoded protein has been found in to correlate with survival in certain carcinomas (PMID: 21102415) and may be important for cellular response to stress (PMID: 21072319). Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
Gene Name:
Chromosome: CHR1: 109656584 -109749403
Locus: 1p13.3
Gene Diseases
The CELSR2 KIAA1324 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
| Uterine Corpus Endometrial Carcinoma |
| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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