CEP164-BACE1 Fusion FISH Probe
The CEP164-BACE1 Fusion FISH Probe is used to confirm a fusion of the CEP164 and BACE1 genes. The fusion of the CEP164 and BACE1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CEP164-BACE1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-RERE | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-REOR | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-REGO | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-REGR | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-REAQ | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-ORRE | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-OROR | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-ORGO | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-GORE | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-GOOR | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-GOGO | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-GOGR | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-GRRE | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-GROR | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-GRGO | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-GRGR | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-AQRE | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-AQOR | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-AQGO | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-AQGR | 20 (40 μL) | 200 μL |
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| CEP164-BACE1-20-AQAQ | 20 (40 μL) | 200 μL |
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CEP164 Gene Summary
This gene encodes a centrosomal protein involved in microtubule organization, DNA damage response, and chromosome segregation. The encoded protein is required for assembly of primary cilia and localizes to mature centrioles. Defects in this gene are a cause of nephronophthisis-related ciliopathies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
Gene Name: Centrosomal Protein 164
Chromosome: CHR11: 117198570 -117283982
Locus: 11q23.3
BACE1 Gene Summary
This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015]
Gene Name: Beta-secretase 1
Chromosome: CHR11: 117156401 -117186972
Locus: 11q23.3
Gene Diseases
The CEP164 BACE1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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