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CFTR-ASZ1 Fusion FISH Probe

The CFTR-ASZ1 Fusion FISH Probe is used to confirm a fusion of the CFTR and ASZ1 genes. The fusion of the CFTR and ASZ1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CFTR-ASZ1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CFTR-ASZ1-20-RERE 20 (40 μL) 200 μL
CFTR-ASZ1-20-REOR 20 (40 μL) 200 μL
CFTR-ASZ1-20-REGO 20 (40 μL) 200 μL
CFTR-ASZ1-20-REGR 20 (40 μL) 200 μL
CFTR-ASZ1-20-REAQ 20 (40 μL) 200 μL
CFTR-ASZ1-20-ORRE 20 (40 μL) 200 μL
CFTR-ASZ1-20-OROR 20 (40 μL) 200 μL
CFTR-ASZ1-20-ORGO 20 (40 μL) 200 μL
CFTR-ASZ1-20-ORAQ 20 (40 μL) 200 μL
CFTR-ASZ1-20-GORE 20 (40 μL) 200 μL
CFTR-ASZ1-20-GOOR 20 (40 μL) 200 μL
CFTR-ASZ1-20-GOGO 20 (40 μL) 200 μL
CFTR-ASZ1-20-GOGR 20 (40 μL) 200 μL
CFTR-ASZ1-20-GOAQ 20 (40 μL) 200 μL
CFTR-ASZ1-20-GRRE 20 (40 μL) 200 μL
CFTR-ASZ1-20-GROR 20 (40 μL) 200 μL
CFTR-ASZ1-20-GRGO 20 (40 μL) 200 μL
CFTR-ASZ1-20-GRGR 20 (40 μL) 200 μL
CFTR-ASZ1-20-GRAQ 20 (40 μL) 200 μL
CFTR-ASZ1-20-AQRE 20 (40 μL) 200 μL
CFTR-ASZ1-20-AQOR 20 (40 μL) 200 μL
CFTR-ASZ1-20-AQGO 20 (40 μL) 200 μL
CFTR-ASZ1-20-AQGR 20 (40 μL) 200 μL
CFTR-ASZ1-20-AQAQ 20 (40 μL) 200 μL

CFTR Gene Summary

This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. The encoded protein functions as a chloride channel, making it unique among members of this protein family, and controls ion and water secretion and absorption in epithelial tissues. Channel activation is mediated by cycles of regulatory domain phosphorylation, ATP-binding by the nucleotide-binding domains, and ATP hydrolysis. Mutations in this gene cause cystic fibrosis, the most common lethal genetic disorder in populations of Northern European descent. The most frequently occurring mutation in cystic fibrosis, DeltaF508, results in impaired folding and trafficking of the encoded protein. Multiple pseudogenes have been identified in the human genome. [provided by RefSeq, Aug 2017]

Gene Name: Cystic Fibrosis Transmembrane Conductance Regulator

Chromosome: CHR7: 117120016 -117308718

Locus: 7q31.2

ASZ1 Gene Summary

The Ankyrin Repeat, SAM And Basic Leucine Zipper Domain Containing 1 (ASZ1) gene is located on chr7 :117003275-117067577 at 7q31.2.

Gene Name: Ankyrin Repeat, SAM And Basic Leucine Zipper Domain Containing 1

Chromosome: CHR7: 117003275 -117067577

Locus: 7q31.2

Gene Diseases

The CFTR ASZ1 Fusion has been associated with the following diseases:

Disease Name
Brain Lower Grade Glioma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.