CHAF1B-DOPEY2 Fusion FISH Probe
The CHAF1B-DOPEY2 Fusion FISH Probe is used to confirm a fusion of the CHAF1B and DOPEY2 genes. The fusion of the CHAF1B and DOPEY2 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHAF1B-DOPEY2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-RERE | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-REOR | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-REGO | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-REGR | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-REAQ | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-ORRE | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-OROR | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-ORGO | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-GORE | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-GOOR | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-GOGO | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-GOGR | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-GRRE | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-GROR | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-GRGO | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-GRGR | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-AQRE | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-AQOR | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-AQGO | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-AQGR | 20 (40 μL) | 200 μL |
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| CHAF1B-DOPEY2-20-AQAQ | 20 (40 μL) | 200 μL |
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CHAF1B Gene Summary
Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. [provided by RefSeq, Jul 2008]
Gene Name: Chromatin Assembly Factor 1 Subunit B
Chromosome: CHR21: 37757688 -37789125
Locus: 21q22.12-q22.13
DOPEY2 Gene Summary
The Dopey Family Member 2 (DOPEY2) gene is located on chr21 :37536838-37666572 at 21q22.12.
Gene Name: Dopey Family Member 2
Chromosome: CHR21: 37536838 -37666572
Locus: 21q22.12
Gene Diseases
The CHAF1B DOPEY2 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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