CHI3L1-APOA2 Fusion FISH Probe
The CHI3L1-APOA2 Fusion FISH Probe is used to confirm a fusion of the CHI3L1 and APOA2 genes. The fusion of the CHI3L1 and APOA2 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHI3L1-APOA2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-RERE | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-REOR | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-REGO | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-REGR | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-REAQ | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-ORRE | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-OROR | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-ORGO | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-GORE | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-GOOR | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-GOGO | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-GOGR | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-GRRE | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-GROR | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-GRGO | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-GRGR | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-AQRE | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-AQOR | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-AQGO | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-AQGR | 20 (40 μL) | 200 μL |
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| CHI3L1-APOA2-20-AQAQ | 20 (40 μL) | 200 μL |
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APOA2 Gene Summary
This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008]
Gene Name: Apolipoprotein A2
Chromosome: CHR1: 161192082 -161193418
Locus: 1q23.3
CHI3L1 Gene Summary
Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling. [provided by RefSeq, Sep 2009]
Gene Name: Chitinase 3 Like 1
Chromosome: CHR1: 203148058 -203155922
Locus: 1q32.1
Gene Diseases
The CHI3L1 APOA2 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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