CHIC2-MANBA Fusion FISH Probe
The CHIC2-MANBA Fusion FISH Probe is used to confirm a fusion of the CHIC2 and MANBA genes. The fusion of the CHIC2 and MANBA genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHIC2-MANBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-RERE | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-REOR | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-REGO | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-REGR | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-REAQ | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-ORRE | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-OROR | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-ORGO | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-ORAQ | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-GORE | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-GOOR | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-GOGO | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-GOGR | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-GOAQ | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-GRRE | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-GROR | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-GRGO | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-GRGR | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-GRAQ | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-AQRE | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-AQOR | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-AQGO | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-AQGR | 20 (40 μL) | 200 μL |
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| CHIC2-MANBA-20-AQAQ | 20 (40 μL) | 200 μL |
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MANBA Gene Summary
This gene encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement. [provided by RefSeq, Jul 2008]
Gene Name: Mannosidase Beta
Chromosome: CHR4: 103552642 -103682151
Locus: 4q24
CHIC2 Gene Summary
This gene encodes a member of the CHIC family of proteins. The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane. This gene is associated with some cases of acute myeloid leukemia. [provided by RefSeq, Jul 2008]
Gene Name: Cysteine Rich Hydrophobic Domain 2
Chromosome: CHR4: 54875957 -54930815
Locus: 4q12
Gene Diseases
The CHIC2 MANBA Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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