CNOT6-TSPAN8 Fusion FISH Probe
The CNOT6-TSPAN8 Fusion FISH Probe is used to confirm a fusion of the CNOT6 and TSPAN8 genes. The fusion of the CNOT6 and TSPAN8 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CNOT6-TSPAN8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-RERE | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-REOR | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-REGO | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-REGR | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-REAQ | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-ORRE | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-OROR | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-ORGO | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-ORAQ | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-GORE | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-GOOR | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-GOGO | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-GOGR | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-GOAQ | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-GRRE | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-GROR | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-GRGO | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-GRGR | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-GRAQ | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-AQRE | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-AQOR | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-AQGO | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-AQGR | 20 (40 μL) | 200 μL |
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| CNOT6-TSPAN8-20-AQAQ | 20 (40 μL) | 200 μL |
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TSPAN8 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Tetraspanin 8
Chromosome: CHR12: 71518876 -71551779
Locus: 12q21.1
CNOT6 Gene Summary
This gene encodes the catalytic component of the CCR4-NOT core transcriptional regulation complex. The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substrates. The CCR4-NOT complex plays a role in many cellular processes, including miRNA-mediated repression, mRNA degradation, and transcriptional regulation. [provided by RefSeq, Dec 2014]
Gene Name: CCR4-NOT Transcription Complex Subunit 6
Chromosome: CHR5: 179921416 -180005353
Locus: 5q35.3
Gene Diseases
The CNOT6 TSPAN8 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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