CNTNAP2-GSTK1 Fusion FISH Probe
The CNTNAP2-GSTK1 Fusion FISH Probe is used to confirm a fusion of the CNTNAP2 and GSTK1 genes. The fusion of the CNTNAP2 and GSTK1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CNTNAP2-GSTK1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-RERE | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-REOR | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-REGO | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-REGR | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-REAQ | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-ORRE | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-OROR | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-ORGO | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-GORE | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-GOOR | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-GOGO | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-GOGR | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-GRRE | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-GROR | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-GRGO | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-GRGR | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-AQRE | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-AQOR | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-AQGO | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-AQGR | 20 (40 μL) | 200 μL |
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| CNTNAP2-GSTK1-20-AQAQ | 20 (40 μL) | 200 μL |
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CNTNAP2 Gene Summary
This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2, a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and intellectual disability. [provided by RefSeq, Jul 2017]
Gene Name: Contactin Associated Protein Like 2
Chromosome: CHR7: 145813452 -148118088
Locus: 7q35-q36.1
GSTK1 Gene Summary
This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]
Gene Name: Glutathione S-transferase Kappa 1
Chromosome: CHR7: 142960521 -142966222
Locus: 7q34
Gene Diseases
The CNTNAP2 GSTK1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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