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COBRA1-FBXW5 Fusion FISH Probe

The COBRA1-FBXW5 Fusion FISH Probe is used to confirm a fusion of the COBRA1 and FBXW5 genes. The fusion of the COBRA1 and FBXW5 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
COBRA1-FBXW5-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
COBRA1-FBXW5-20-RERE 20 (40 μL) 200 μL
COBRA1-FBXW5-20-REOR 20 (40 μL) 200 μL
COBRA1-FBXW5-20-REGO 20 (40 μL) 200 μL
COBRA1-FBXW5-20-REGR 20 (40 μL) 200 μL
COBRA1-FBXW5-20-REAQ 20 (40 μL) 200 μL
COBRA1-FBXW5-20-ORRE 20 (40 μL) 200 μL
COBRA1-FBXW5-20-OROR 20 (40 μL) 200 μL
COBRA1-FBXW5-20-ORGO 20 (40 μL) 200 μL
COBRA1-FBXW5-20-ORAQ 20 (40 μL) 200 μL
COBRA1-FBXW5-20-GORE 20 (40 μL) 200 μL
COBRA1-FBXW5-20-GOOR 20 (40 μL) 200 μL
COBRA1-FBXW5-20-GOGO 20 (40 μL) 200 μL
COBRA1-FBXW5-20-GOGR 20 (40 μL) 200 μL
COBRA1-FBXW5-20-GOAQ 20 (40 μL) 200 μL
COBRA1-FBXW5-20-GRRE 20 (40 μL) 200 μL
COBRA1-FBXW5-20-GROR 20 (40 μL) 200 μL
COBRA1-FBXW5-20-GRGO 20 (40 μL) 200 μL
COBRA1-FBXW5-20-GRGR 20 (40 μL) 200 μL
COBRA1-FBXW5-20-GRAQ 20 (40 μL) 200 μL
COBRA1-FBXW5-20-AQRE 20 (40 μL) 200 μL
COBRA1-FBXW5-20-AQOR 20 (40 μL) 200 μL
COBRA1-FBXW5-20-AQGO 20 (40 μL) 200 μL
COBRA1-FBXW5-20-AQGR 20 (40 μL) 200 μL
COBRA1-FBXW5-20-AQAQ 20 (40 μL) 200 μL

FBXW5 Gene Summary

This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented. [provided by RefSeq, Jul 2008]

Gene Name: F-box And WD Repeat Domain Containing 5

Chromosome: CHR9: 139834886 -139839173

Locus: 9q34.3

Gene Diseases

The COBRA1 FBXW5 Fusion has been associated with the following diseases:

Disease Name
Esophageal Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.