COQ10A-USP5 Fusion FISH Probe
The COQ10A-USP5 Fusion FISH Probe is used to confirm a fusion of the COQ10A and USP5 genes. The fusion of the COQ10A and USP5 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| COQ10A-USP5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-RERE | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-REOR | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-REGO | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-REGR | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-REAQ | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-ORRE | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-OROR | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-ORGO | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-ORAQ | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-GORE | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-GOOR | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-GOGO | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-GOGR | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-GOAQ | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-GRRE | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-GROR | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-GRGO | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-GRGR | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-GRAQ | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-AQRE | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-AQOR | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-AQGO | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-AQGR | 20 (40 μL) | 200 μL |
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| COQ10A-USP5-20-AQAQ | 20 (40 μL) | 200 μL |
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USP5 Gene Summary
Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM, Mar 2010]
Gene Name: Ubiquitin Specific Peptidase 5
Chromosome: CHR12: 6961284 -6975795
Locus: 12p13.31
COQ10A Gene Summary
The Coenzyme Q10A (COQ10A) gene is located on chr12 :56660641-56664750 at 12q13.3.
Gene Name: Coenzyme Q10A
Chromosome: CHR12: 56660641 -56664750
Locus: 12q13.3
Gene Diseases
The COQ10A USP5 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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