COQ6-FLRT1 Fusion FISH Probe
The COQ6-FLRT1 Fusion FISH Probe is used to confirm a fusion of the COQ6 and FLRT1 genes. The fusion of the COQ6 and FLRT1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| COQ6-FLRT1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-RERE | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-REOR | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-REGO | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-REGR | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-REAQ | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-ORRE | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-OROR | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-ORGO | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-ORAQ | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-GORE | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-GOOR | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-GOGO | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-GOGR | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-GOAQ | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-GRRE | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-GROR | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-GRGO | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-GRGR | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-GRAQ | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-AQRE | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-AQOR | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-AQGO | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-AQGR | 20 (40 μL) | 200 μL |
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| COQ6-FLRT1-20-AQAQ | 20 (40 μL) | 200 μL |
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FLRT1 Gene Summary
This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. The encoded protein shares sequence similarity with two other family members, FLRT2 and FLRT3. This gene is expressed in kidney and brain. [provided by RefSeq, Jul 2008]
Gene Name: Fibronectin Leucine Rich Transmembrane Protein 1
Chromosome: CHR11: 63871361 -63886645
Locus: 11q13.1
COQ6 Gene Summary
The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2012]
Gene Name: Coenzyme Q6, Monooxygenase
Chromosome: CHR14: 74416636 -74429813
Locus: 14q24.3
Gene Diseases
The COQ6 FLRT1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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