CORO1C-PACRG Fusion FISH Probe
The CORO1C-PACRG Fusion FISH Probe is used to confirm a fusion of the CORO1C and PACRG genes. The fusion of the CORO1C and PACRG genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CORO1C-PACRG-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-RERE | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-REOR | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-REGO | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-REGR | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-REAQ | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-ORRE | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-OROR | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-ORGO | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-ORAQ | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-GORE | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-GOOR | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-GOGO | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-GOGR | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-GOAQ | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-GRRE | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-GROR | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-GRGO | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-GRGR | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-GRAQ | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-AQRE | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-AQOR | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-AQGO | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-AQGR | 20 (40 μL) | 200 μL |
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| CORO1C-PACRG-20-AQAQ | 20 (40 μL) | 200 μL |
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CORO1C Gene Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]
Gene Name: Coronin 1C
Chromosome: CHR12: 109038886 -109125295
Locus: 12q24.11
PACRG Gene Summary
This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Parkin Coregulated
Chromosome: CHR6: 163148163 -163736524
Locus: 6q26
Gene Diseases
The CORO1C PACRG Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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