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CORO7-TRAF7 Fusion FISH Probe

The CORO7-TRAF7 Fusion FISH Probe is used to confirm a fusion of the CORO7 and TRAF7 genes. The fusion of the CORO7 and TRAF7 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CORO7-TRAF7-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CORO7-TRAF7-20-RERE 20 (40 μL) 200 μL
CORO7-TRAF7-20-REOR 20 (40 μL) 200 μL
CORO7-TRAF7-20-REGO 20 (40 μL) 200 μL
CORO7-TRAF7-20-REGR 20 (40 μL) 200 μL
CORO7-TRAF7-20-REAQ 20 (40 μL) 200 μL
CORO7-TRAF7-20-ORRE 20 (40 μL) 200 μL
CORO7-TRAF7-20-OROR 20 (40 μL) 200 μL
CORO7-TRAF7-20-ORGO 20 (40 μL) 200 μL
CORO7-TRAF7-20-ORAQ 20 (40 μL) 200 μL
CORO7-TRAF7-20-GORE 20 (40 μL) 200 μL
CORO7-TRAF7-20-GOOR 20 (40 μL) 200 μL
CORO7-TRAF7-20-GOGO 20 (40 μL) 200 μL
CORO7-TRAF7-20-GOGR 20 (40 μL) 200 μL
CORO7-TRAF7-20-GOAQ 20 (40 μL) 200 μL
CORO7-TRAF7-20-GRRE 20 (40 μL) 200 μL
CORO7-TRAF7-20-GROR 20 (40 μL) 200 μL
CORO7-TRAF7-20-GRGO 20 (40 μL) 200 μL
CORO7-TRAF7-20-GRGR 20 (40 μL) 200 μL
CORO7-TRAF7-20-GRAQ 20 (40 μL) 200 μL
CORO7-TRAF7-20-AQRE 20 (40 μL) 200 μL
CORO7-TRAF7-20-AQOR 20 (40 μL) 200 μL
CORO7-TRAF7-20-AQGO 20 (40 μL) 200 μL
CORO7-TRAF7-20-AQGR 20 (40 μL) 200 μL
CORO7-TRAF7-20-AQAQ 20 (40 μL) 200 μL

CORO7 Gene Summary

This gene encodes a member of the coronin protein family. However, unlike other coronin proteins, it is not an actin-binding protein but rather functions as an F-actin regulator directing anterograde Golgi to endosome transport. The encoded protein has two tandem WD-40 domain repeats and localizes to the trans-Golgi network. The protein undergoes K33-linked polyubiquitination via an E3 ligase complex. It is thought to play an essential role in maintenance of Golgi apparatus morphology. Alternative splicing results in multiple transcripts variants; some of which form read-through transcripts with a neighboring gene. [provided by RefSeq, Dec 2016]

Gene Name: Coronin 7

Chromosome: CHR16: 4404542 -4466962

Locus: 16p13.3

TRAF7 Gene Summary

Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.[supplied by OMIM, Apr 2004]

Gene Name: TNF Receptor Associated Factor 7

Chromosome: CHR16: 2205798 -2228130

Locus: 16p13.3

Gene Diseases

The CORO7 TRAF7 Fusion has been associated with the following diseases:

Disease Name
Brain Lower Grade Glioma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.