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CPB1-NDUFV1 Fusion FISH Probe

The CPB1-NDUFV1 Fusion FISH Probe is used to confirm a fusion of the CPB1 and NDUFV1 genes. The fusion of the CPB1 and NDUFV1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CPB1-NDUFV1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CPB1-NDUFV1-20-RERE 20 (40 μL) 200 μL
CPB1-NDUFV1-20-REOR 20 (40 μL) 200 μL
CPB1-NDUFV1-20-REGO 20 (40 μL) 200 μL
CPB1-NDUFV1-20-REGR 20 (40 μL) 200 μL
CPB1-NDUFV1-20-REAQ 20 (40 μL) 200 μL
CPB1-NDUFV1-20-ORRE 20 (40 μL) 200 μL
CPB1-NDUFV1-20-OROR 20 (40 μL) 200 μL
CPB1-NDUFV1-20-ORGO 20 (40 μL) 200 μL
CPB1-NDUFV1-20-ORAQ 20 (40 μL) 200 μL
CPB1-NDUFV1-20-GORE 20 (40 μL) 200 μL
CPB1-NDUFV1-20-GOOR 20 (40 μL) 200 μL
CPB1-NDUFV1-20-GOGO 20 (40 μL) 200 μL
CPB1-NDUFV1-20-GOGR 20 (40 μL) 200 μL
CPB1-NDUFV1-20-GOAQ 20 (40 μL) 200 μL
CPB1-NDUFV1-20-GRRE 20 (40 μL) 200 μL
CPB1-NDUFV1-20-GROR 20 (40 μL) 200 μL
CPB1-NDUFV1-20-GRGO 20 (40 μL) 200 μL
CPB1-NDUFV1-20-GRGR 20 (40 μL) 200 μL
CPB1-NDUFV1-20-GRAQ 20 (40 μL) 200 μL
CPB1-NDUFV1-20-AQRE 20 (40 μL) 200 μL
CPB1-NDUFV1-20-AQOR 20 (40 μL) 200 μL
CPB1-NDUFV1-20-AQGO 20 (40 μL) 200 μL
CPB1-NDUFV1-20-AQGR 20 (40 μL) 200 μL
CPB1-NDUFV1-20-AQAQ 20 (40 μL) 200 μL

CPB1 Gene Summary

Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. [provided by RefSeq, Jul 2008]

Gene Name: Carboxypeptidase B1

Chromosome: CHR3: 148545587 -148577972

Locus: 3q24

NDUFV1 Gene Summary

The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]

Gene Name: NADH:ubiquinone Oxidoreductase Core Subunit V1

Chromosome: CHR11: 67374322 -67380012

Locus: 11q13.2

Gene Diseases

The CPB1 NDUFV1 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.