CPD-PDE4D Fusion FISH Probe
The CPD-PDE4D Fusion FISH Probe is used to confirm a fusion of the CPD and PDE4D genes. The fusion of the CPD and PDE4D genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CPD-PDE4D-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-RERE | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-REOR | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-REGO | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-REGR | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-REAQ | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-ORRE | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-OROR | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-ORGO | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-ORAQ | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-GORE | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-GOOR | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-GOGO | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-GOGR | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-GOAQ | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-GRRE | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-GROR | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-GRGO | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-GRGR | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-GRAQ | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-AQRE | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-AQOR | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-AQGO | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-AQGR | 20 (40 μL) | 200 μL |
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| CPD-PDE4D-20-AQAQ | 20 (40 μL) | 200 μL |
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CPD Gene Summary
The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Carboxypeptidase D
Chromosome: CHR17: 28705941 -28796675
Locus: 17q11.2
PDE4D Gene Summary
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009]
Gene Name: Phosphodiesterase 4D
Chromosome: CHR5: 58264865 -59783925
Locus: 5q11.2-q12.1
Gene Diseases
The CPD PDE4D Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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