CPEB2-LDB2 Fusion FISH Probe
The CPEB2-LDB2 Fusion FISH Probe is used to confirm a fusion of the CPEB2 and LDB2 genes. The fusion of the CPEB2 and LDB2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CPEB2-LDB2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-RERE | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-REOR | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-REGO | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-REGR | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-REAQ | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-ORRE | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-OROR | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-ORGO | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-GORE | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-GOOR | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-GOGO | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-GOGR | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-GRRE | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-GROR | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-GRGO | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-GRGR | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-AQRE | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-AQOR | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-AQGO | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-AQGR | 20 (40 μL) | 200 μL |
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| CPEB2-LDB2-20-AQAQ | 20 (40 μL) | 200 μL |
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LDB2 Gene Summary
The protein encoded by this gene belongs to the LIM-domain binding family. Members of this family are characterized by a conserved nuclear localization sequence, an amino-terminal homodimerization domain and a carboxy-terminal LIM interaction domain. These proteins function as adapter molecules to allow assembly of transcriptional regulatory complexes. Genetic association studies suggest functions for this gene in rhegmatogenous retinal detachment and coronary artery disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Gene Name: LIM Domain Binding 2
Chromosome: CHR4: 16503164 -16900424
Locus: 4p15.32
CPEB2 Gene Summary
The protein encoded by this gene is highly similar to cytoplasmic polyadenylation element binding protein (CPEB), an mRNA-binding protein that regulates cytoplasmic polyadenylation of mRNA as a trans factor in oogenesis and spermatogenesis. Studies of the similar gene in mice suggested a possible role of this protein in transcriptionally inactive haploid spermatids. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: Cytoplasmic Polyadenylation Element Binding Protein 2
Chromosome: CHR4: 15004297 -15071777
Locus: 4p15.32
Gene Diseases
The CPEB2 LDB2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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