CRADD-GRIP1 Fusion FISH Probe
The CRADD-GRIP1 Fusion FISH Probe is used to confirm a fusion of the CRADD and GRIP1 genes. The fusion of the CRADD and GRIP1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CRADD-GRIP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-RERE | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-REOR | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-REGO | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-REGR | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-REAQ | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-ORRE | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-OROR | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-ORGO | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-GORE | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-GOOR | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-GOGO | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-GOGR | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-GRRE | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-GROR | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-GRGO | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-GRGR | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-AQRE | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-AQOR | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-AQGO | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-AQGR | 20 (40 μL) | 200 μL |
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| CRADD-GRIP1-20-AQAQ | 20 (40 μL) | 200 μL |
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CRADD Gene Summary
This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Name: CASP2 And RIPK1 Domain Containing Adaptor With Death Domain
Chromosome: CHR12: 94071150 -94244531
Locus: 12q22
GRIP1 Gene Summary
This gene encodes a member of the glutamate receptor interacting protein family. The encoded scaffold protein binds to and mediates the trafficking and membrane organization of a number of transmembrane proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, May 2010]
Gene Name: Glutamate Receptor Interacting Protein 1
Chromosome: CHR12: 66741210 -67072925
Locus: 12q14.3
Gene Diseases
The CRADD GRIP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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