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CREBL2-GPR19 Fusion FISH Probe

The CREBL2-GPR19 Fusion FISH Probe is used to confirm a fusion of the CREBL2 and GPR19 genes. The fusion of the CREBL2 and GPR19 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CREBL2-GPR19-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CREBL2-GPR19-20-RERE 20 (40 μL) 200 μL
CREBL2-GPR19-20-REOR 20 (40 μL) 200 μL
CREBL2-GPR19-20-REGO 20 (40 μL) 200 μL
CREBL2-GPR19-20-REGR 20 (40 μL) 200 μL
CREBL2-GPR19-20-REAQ 20 (40 μL) 200 μL
CREBL2-GPR19-20-ORRE 20 (40 μL) 200 μL
CREBL2-GPR19-20-OROR 20 (40 μL) 200 μL
CREBL2-GPR19-20-ORGO 20 (40 μL) 200 μL
CREBL2-GPR19-20-ORAQ 20 (40 μL) 200 μL
CREBL2-GPR19-20-GORE 20 (40 μL) 200 μL
CREBL2-GPR19-20-GOOR 20 (40 μL) 200 μL
CREBL2-GPR19-20-GOGO 20 (40 μL) 200 μL
CREBL2-GPR19-20-GOGR 20 (40 μL) 200 μL
CREBL2-GPR19-20-GOAQ 20 (40 μL) 200 μL
CREBL2-GPR19-20-GRRE 20 (40 μL) 200 μL
CREBL2-GPR19-20-GROR 20 (40 μL) 200 μL
CREBL2-GPR19-20-GRGO 20 (40 μL) 200 μL
CREBL2-GPR19-20-GRGR 20 (40 μL) 200 μL
CREBL2-GPR19-20-GRAQ 20 (40 μL) 200 μL
CREBL2-GPR19-20-AQRE 20 (40 μL) 200 μL
CREBL2-GPR19-20-AQOR 20 (40 μL) 200 μL
CREBL2-GPR19-20-AQGO 20 (40 μL) 200 μL
CREBL2-GPR19-20-AQGR 20 (40 μL) 200 μL
CREBL2-GPR19-20-AQAQ 20 (40 μL) 200 μL

CREBL2 Gene Summary

cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. [provided by RefSeq, Jul 2008]

Gene Name: CAMP Responsive Element Binding Protein Like 2

Chromosome: CHR12: 12764830 -12798041

Locus: 12p13.1

GPR19 Gene Summary

The G Protein-coupled Receptor 19 (GPR19) gene is located on chr12 :12813994-12849121 at 12p13.1.

Gene Name: G Protein-coupled Receptor 19

Chromosome: CHR12: 12813994 -12849121

Locus: 12p13.1

Gene Diseases

The CREBL2 GPR19 Fusion has been associated with the following diseases:

Disease Name
Bladder Urothelial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.