CRTC1-KCNN1 Fusion FISH Probe
The CRTC1-KCNN1 Fusion FISH Probe is used to confirm a fusion of the CRTC1 and KCNN1 genes. The fusion of the CRTC1 and KCNN1 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CRTC1-KCNN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-RERE | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-REOR | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-REGO | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-REGR | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-REAQ | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-ORRE | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-OROR | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-ORGO | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-GORE | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-GOOR | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-GOGO | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-GOGR | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-GRRE | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-GROR | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-GRGO | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-GRGR | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-AQRE | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-AQOR | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-AQGO | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-AQGR | 20 (40 μL) | 200 μL |
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| CRTC1-KCNN1-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNN1 Gene Summary
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. [provided by RefSeq, Jul 2008]
Gene Name: Potassium Calcium-activated Channel Subfamily N Member 1
Chromosome: CHR19: 18062110 -18109930
Locus: 19p13.11
CRTC1 Gene Summary
The CREB Regulated Transcription Coactivator 1 (CRTC1) gene is located on chr19 :18794424-18893143 at 19p13.11.
Gene Name: CREB Regulated Transcription Coactivator 1
Chromosome: CHR19: 18794424 -18893143
Locus: 19p13.11
Gene Diseases
The CRTC1 KCNN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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