CSAD-ITGB7 Fusion FISH Probe
The CSAD-ITGB7 Fusion FISH Probe is used to confirm a fusion of the CSAD and ITGB7 genes. The fusion of the CSAD and ITGB7 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CSAD-ITGB7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-RERE | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-REOR | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-REGO | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-REGR | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-REAQ | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-ORRE | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-OROR | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-ORGO | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-ORAQ | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-GORE | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-GOOR | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-GOGO | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-GOGR | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-GOAQ | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-GRRE | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-GROR | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-GRGO | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-GRGR | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-GRAQ | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-AQRE | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-AQOR | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-AQGO | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-AQGR | 20 (40 μL) | 200 μL |
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| CSAD-ITGB7-20-AQAQ | 20 (40 μL) | 200 μL |
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ITGB7 Gene Summary
This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]
Gene Name: Integrin Subunit Beta 7
Chromosome: CHR12: 53585106 -53601000
Locus: 12q13.13
CSAD Gene Summary
This gene encodes a member of the group 2 decarboxylase family. A similar protein in rodents plays a role in multiple biological processes as the rate-limiting enzyme in taurine biosynthesis, catalyzing the decarboxylation of cysteinesulfinate to hypotaurine. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Gene Name: Cysteine Sulfinic Acid Decarboxylase
Chromosome: CHR12: 53551446 -53574430
Locus: 12q13.13
Gene Diseases
The CSAD ITGB7 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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