CSAD-NPFF Fusion FISH Probe
The CSAD-NPFF Fusion FISH Probe is used to confirm a fusion of the CSAD and NPFF genes. The fusion of the CSAD and NPFF genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CSAD-NPFF-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-RERE | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-REOR | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-REGO | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-REGR | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-REAQ | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-ORRE | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-OROR | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-ORGO | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-ORAQ | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-GORE | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-GOOR | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-GOGO | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-GOGR | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-GOAQ | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-GRRE | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-GROR | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-GRGO | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-GRGR | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-GRAQ | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-AQRE | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-AQOR | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-AQGO | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-AQGR | 20 (40 μL) | 200 μL |
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| CSAD-NPFF-20-AQAQ | 20 (40 μL) | 200 μL |
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NPFF Gene Summary
This gene encodes a member of the FMRFamide related peptide (FARP) family of neuropeptides. The encoded preproprotein is proteolytically processed to generate multiple amidated peptides. These peptides may play a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. Patients with hypertension exhibit decreased expression of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Gene Name: Neuropeptide FF-amide Peptide Precursor
Chromosome: CHR12: 53900473 -53901422
Locus: 12q13.13
CSAD Gene Summary
This gene encodes a member of the group 2 decarboxylase family. A similar protein in rodents plays a role in multiple biological processes as the rate-limiting enzyme in taurine biosynthesis, catalyzing the decarboxylation of cysteinesulfinate to hypotaurine. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Gene Name: Cysteine Sulfinic Acid Decarboxylase
Chromosome: CHR12: 53551446 -53574430
Locus: 12q13.13
Gene Diseases
The CSAD NPFF Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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