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CSNK1E-DMC1 Fusion FISH Probe

The CSNK1E-DMC1 Fusion FISH Probe is used to confirm a fusion of the CSNK1E and DMC1 genes. The fusion of the CSNK1E and DMC1 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CSNK1E-DMC1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CSNK1E-DMC1-20-RERE 20 (40 μL) 200 μL
CSNK1E-DMC1-20-REOR 20 (40 μL) 200 μL
CSNK1E-DMC1-20-REGO 20 (40 μL) 200 μL
CSNK1E-DMC1-20-REGR 20 (40 μL) 200 μL
CSNK1E-DMC1-20-REAQ 20 (40 μL) 200 μL
CSNK1E-DMC1-20-ORRE 20 (40 μL) 200 μL
CSNK1E-DMC1-20-OROR 20 (40 μL) 200 μL
CSNK1E-DMC1-20-ORGO 20 (40 μL) 200 μL
CSNK1E-DMC1-20-ORAQ 20 (40 μL) 200 μL
CSNK1E-DMC1-20-GORE 20 (40 μL) 200 μL
CSNK1E-DMC1-20-GOOR 20 (40 μL) 200 μL
CSNK1E-DMC1-20-GOGO 20 (40 μL) 200 μL
CSNK1E-DMC1-20-GOGR 20 (40 μL) 200 μL
CSNK1E-DMC1-20-GOAQ 20 (40 μL) 200 μL
CSNK1E-DMC1-20-GRRE 20 (40 μL) 200 μL
CSNK1E-DMC1-20-GROR 20 (40 μL) 200 μL
CSNK1E-DMC1-20-GRGO 20 (40 μL) 200 μL
CSNK1E-DMC1-20-GRGR 20 (40 μL) 200 μL
CSNK1E-DMC1-20-GRAQ 20 (40 μL) 200 μL
CSNK1E-DMC1-20-AQRE 20 (40 μL) 200 μL
CSNK1E-DMC1-20-AQOR 20 (40 μL) 200 μL
CSNK1E-DMC1-20-AQGO 20 (40 μL) 200 μL
CSNK1E-DMC1-20-AQGR 20 (40 μL) 200 μL
CSNK1E-DMC1-20-AQAQ 20 (40 μL) 200 μL

CSNK1E Gene Summary

The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]

Gene Name: Casein Kinase 1 Epsilon

Chromosome: CHR22: 38686696 -38714089

Locus: 22q13.1

DMC1 Gene Summary

This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Gene Name: DNA Meiotic Recombinase 1

Chromosome: CHR22: 38914953 -38966189

Locus: 22q13.1

Gene Diseases

The CSNK1E DMC1 Fusion has been associated with the following diseases:

Disease Name
Uterine Corpus Endometrial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.