CSNK2B-VARS Fusion FISH Probe
The CSNK2B-VARS Fusion FISH Probe is used to confirm a fusion of the CSNK2B and VARS genes. The fusion of the CSNK2B and VARS genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CSNK2B-VARS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-RERE | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-REOR | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-REGO | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-REGR | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-REAQ | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-ORRE | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-OROR | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-ORGO | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-ORAQ | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-GORE | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-GOOR | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-GOGO | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-GOGR | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-GOAQ | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-GRRE | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-GROR | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-GRGO | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-GRGR | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-GRAQ | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-AQRE | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-AQOR | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-AQGO | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-AQGR | 20 (40 μL) | 200 μL |
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| CSNK2B-VARS-20-AQAQ | 20 (40 μL) | 200 μL |
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CSNK2B Gene Summary
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Gene Name: Casein Kinase 2 Beta
Chromosome: CHR6_dbb_hap3: 2919235 -2923423
Locus: 6p21.33
VARS Gene Summary
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]
Gene Name: Valyl-tRNA Synthetase
Chromosome: CHR6_dbb_hap3: 3030878 -3049294
Locus: 6p21.33
Gene Diseases
The CSNK2B VARS Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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