CSPP1-CPA6 Fusion FISH Probe
The CSPP1-CPA6 Fusion FISH Probe is used to confirm a fusion of the CSPP1 and CPA6 genes. The fusion of the CSPP1 and CPA6 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CSPP1-CPA6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-RERE | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-REOR | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-REGO | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-REGR | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-REAQ | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-ORRE | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-OROR | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-ORGO | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-ORAQ | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-GORE | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-GOOR | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-GOGO | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-GOGR | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-GOAQ | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-GRRE | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-GROR | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-GRGO | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-GRGR | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-GRAQ | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-AQRE | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-AQOR | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-AQGO | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-AQGR | 20 (40 μL) | 200 μL |
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| CSPP1-CPA6-20-AQAQ | 20 (40 μL) | 200 μL |
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CPA6 Gene Summary
The gene encodes a member of the peptidase M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature enzyme, which catalyzes the release of large hydrophobic C-terminal amino acids. This enzyme has functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Mutations in this gene may be linked to epilepsy and febrile seizures, and a translocation t(6;8)(q26;q13) involving this gene has been associated with Duane retraction syndrome. [provided by RefSeq, May 2016]
Gene Name: Carboxypeptidase A6
Chromosome: CHR8: 68334404 -68658620
Locus: 8q13.2
CSPP1 Gene Summary
This gene encodes a centrosome and spindle pole associated protein. The encoded protein plays a role in cell-cycle progression and spindle organization, regulates cytokinesis, interacts with Nephrocystin 8 and is required for cilia formation. Mutations in this gene result in primary cilia abnormalities and classical Joubert syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Gene Name: Centrosome And Spindle Pole Associated Protein 1
Chromosome: CHR8: 67976602 -68108849
Locus: 8q13.1-q13.2
Gene Diseases
The CSPP1 CPA6 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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