CSTF1-BLM Fusion FISH Probe
The CSTF1-BLM Fusion FISH Probe is used to confirm a fusion of the CSTF1 and BLM genes. The fusion of the CSTF1 and BLM genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CSTF1-BLM-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-RERE | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-REOR | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-REGO | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-REGR | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-REAQ | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-ORRE | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-OROR | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-ORGO | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-ORAQ | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-GORE | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-GOOR | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-GOGO | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-GOGR | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-GOAQ | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-GRRE | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-GROR | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-GRGO | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-GRGR | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-GRAQ | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-AQRE | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-AQOR | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-AQGO | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-AQGR | 20 (40 μL) | 200 μL |
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| CSTF1-BLM-20-AQAQ | 20 (40 μL) | 200 μL |
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BLM Gene Summary
The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination. [provided by RefSeq, Jul 2008]
Gene Name: Bloom Syndrome RecQ Like Helicase
Chromosome: CHR15: 91260578 -91358686
Locus: 15q26.1
CSTF1 Gene Summary
This gene encodes one of three subunits which combine to form cleavage stimulation factor (CSTF). CSTF is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. Similar to mammalian G protein beta subunits, this protein contains transducin-like repeats. Several transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Cleavage Stimulation Factor Subunit 1
Chromosome: CHR20: 54967426 -54979582
Locus: 20q13.2-q13.31
Gene Diseases
The CSTF1 BLM Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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