CTBP1-POLN Fusion FISH Probe
The CTBP1-POLN Fusion FISH Probe is used to confirm a fusion of the CTBP1 and POLN genes. The fusion of the CTBP1 and POLN genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CTBP1-POLN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-RERE | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-REOR | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-REGO | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-REGR | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-REAQ | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-ORRE | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-OROR | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-ORGO | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-ORAQ | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-GORE | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-GOOR | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-GOGO | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-GOGR | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-GOAQ | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-GRRE | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-GROR | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-GRGO | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-GRGR | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-GRAQ | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-AQRE | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-AQOR | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-AQGO | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-AQGR | 20 (40 μL) | 200 μL |
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| CTBP1-POLN-20-AQAQ | 20 (40 μL) | 200 μL |
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CTBP1 Gene Summary
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Name: C-terminal Binding Protein 1
Chromosome: CHR4: 1205227 -1242908
Locus: 4p16.3
POLN Gene Summary
This gene encodes a DNA polymerase type-A family member. The encoded protein plays a role in DNA repair and homologous recombination. This gene shares its 5' exons with some transcripts from overlapping GeneID: 79441, which encodes an augmentin-like protein complex subunit. [provided by RefSeq, Dec 2014]
Gene Name: DNA Polymerase Nu
Chromosome: CHR4: 2073644 -2230958
Locus: 4p16.3
Gene Diseases
The CTBP1 POLN Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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