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CTDP1-NFATC1 Fusion FISH Probe

The CTDP1-NFATC1 Fusion FISH Probe is used to confirm a fusion of the CTDP1 and NFATC1 genes. The fusion of the CTDP1 and NFATC1 genes has been associated with Acute Myeloid Leukemia, and Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CTDP1-NFATC1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CTDP1-NFATC1-20-RERE 20 (40 μL) 200 μL
CTDP1-NFATC1-20-REOR 20 (40 μL) 200 μL
CTDP1-NFATC1-20-REGO 20 (40 μL) 200 μL
CTDP1-NFATC1-20-REGR 20 (40 μL) 200 μL
CTDP1-NFATC1-20-REAQ 20 (40 μL) 200 μL
CTDP1-NFATC1-20-ORRE 20 (40 μL) 200 μL
CTDP1-NFATC1-20-OROR 20 (40 μL) 200 μL
CTDP1-NFATC1-20-ORGO 20 (40 μL) 200 μL
CTDP1-NFATC1-20-ORAQ 20 (40 μL) 200 μL
CTDP1-NFATC1-20-GORE 20 (40 μL) 200 μL
CTDP1-NFATC1-20-GOOR 20 (40 μL) 200 μL
CTDP1-NFATC1-20-GOGO 20 (40 μL) 200 μL
CTDP1-NFATC1-20-GOGR 20 (40 μL) 200 μL
CTDP1-NFATC1-20-GOAQ 20 (40 μL) 200 μL
CTDP1-NFATC1-20-GRRE 20 (40 μL) 200 μL
CTDP1-NFATC1-20-GROR 20 (40 μL) 200 μL
CTDP1-NFATC1-20-GRGO 20 (40 μL) 200 μL
CTDP1-NFATC1-20-GRGR 20 (40 μL) 200 μL
CTDP1-NFATC1-20-GRAQ 20 (40 μL) 200 μL
CTDP1-NFATC1-20-AQRE 20 (40 μL) 200 μL
CTDP1-NFATC1-20-AQOR 20 (40 μL) 200 μL
CTDP1-NFATC1-20-AQGO 20 (40 μL) 200 μL
CTDP1-NFATC1-20-AQGR 20 (40 μL) 200 μL
CTDP1-NFATC1-20-AQAQ 20 (40 μL) 200 μL

NFATC1 Gene Summary

The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq, Jul 2013]

Gene Name: Nuclear Factor Of Activated T-cells 1

Chromosome: CHR18: 77155771 -77289323

Locus: 18q23

CTDP1 Gene Summary

This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]

Gene Name: CTD Phosphatase Subunit 1

Chromosome: CHR18: 77439800 -77514510

Locus: 18q23

Gene Diseases

The CTDP1 NFATC1 Fusion has been associated with the following diseases:

Disease Name
Acute Myeloid Leukemia
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.