CTNNA1-EGR1 Fusion FISH Probe
The CTNNA1-EGR1 Fusion FISH Probe is used to confirm a fusion of the CTNNA1 and EGR1 genes. The fusion of the CTNNA1 and EGR1 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CTNNA1-EGR1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-RERE | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-REOR | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-REGO | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-REGR | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-REAQ | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-ORRE | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-OROR | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-ORGO | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-GORE | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-GOOR | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-GOGO | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-GOGR | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-GRRE | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-GROR | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-GRGO | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-GRGR | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-AQRE | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-AQOR | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-AQGO | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-AQGR | 20 (40 μL) | 200 μL |
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| CTNNA1-EGR1-20-AQAQ | 20 (40 μL) | 200 μL |
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CTNNA1 Gene Summary
This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy. [provided by RefSeq, May 2016]
Gene Name: Catenin Alpha 1
Chromosome: CHR5: 138089106 -138270723
Locus: 5q31.2
EGR1 Gene Summary
The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014]
Gene Name: Early Growth Response 1
Chromosome: CHR5: 137801180 -137805004
Locus: 5q31.2
Gene Diseases
The CTNNA1 EGR1 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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