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CTNNB1-SLC38A5 Fusion FISH Probe

The CTNNB1-SLC38A5 Fusion FISH Probe is used to confirm a fusion of the CTNNB1 and SLC38A5 genes. The fusion of the CTNNB1 and SLC38A5 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CTNNB1-SLC38A5-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-RERE 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-REOR 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-REGO 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-REGR 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-REAQ 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-ORRE 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-OROR 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-ORGO 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-ORAQ 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-GORE 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-GOOR 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-GOGO 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-GOGR 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-GOAQ 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-GRRE 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-GROR 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-GRGO 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-GRGR 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-GRAQ 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-AQRE 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-AQOR 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-AQGO 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-AQGR 20 (40 μL) 200 μL
CTNNB1-SLC38A5-20-AQAQ 20 (40 μL) 200 μL

CTNNB1 Gene Summary

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]

Gene Name: Catenin Beta 1

Chromosome: CHR3: 41240941 -41281939

Locus: 3p22.1

SLC38A5 Gene Summary

The protein encoded by this gene is a system N sodium-coupled amino acid transporter. The encoded protein transports glutamine, asparagine, histidine, serine, alanine, and glycine across the cell membrane, but does not transport charged amino acids, imino acids, or N-alkylated amino acids. Alternative splicing results in multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Aug 2013]

Gene Name: Solute Carrier Family 38 Member 5

Chromosome: CHRX: 48316926 -48328644

Locus: Xp11.23

Gene Diseases

The CTNNB1 SLC38A5 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.