CTNND2-P4HA2 Fusion FISH Probe
The CTNND2-P4HA2 Fusion FISH Probe is used to confirm a fusion of the CTNND2 and P4HA2 genes. The fusion of the CTNND2 and P4HA2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CTNND2-P4HA2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-RERE | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-REOR | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-REGO | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-REGR | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-REAQ | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-ORRE | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-OROR | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-ORGO | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-GORE | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-GOOR | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-GOGO | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-GOGR | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-GRRE | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-GROR | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-GRGO | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-GRGR | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-AQRE | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-AQOR | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-AQGO | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-AQGR | 20 (40 μL) | 200 μL |
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| CTNND2-P4HA2-20-AQAQ | 20 (40 μL) | 200 μL |
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CTNND2 Gene Summary
This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
Gene Name: Catenin Delta 2
Chromosome: CHR5: 10971951 -11904110
Locus: 5p15.2
P4HA2 Gene Summary
This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: Prolyl 4-hydroxylase Subunit Alpha 2
Chromosome: CHR5: 131528303 -131563556
Locus: 5q31.1
Gene Diseases
The CTNND2 P4HA2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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