CTSF-RANBP3 Fusion FISH Probe
The CTSF-RANBP3 Fusion FISH Probe is used to confirm a fusion of the CTSF and RANBP3 genes. The fusion of the CTSF and RANBP3 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CTSF-RANBP3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-RERE | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-REOR | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-REGO | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-REGR | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-OROR | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-GORE | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-GROR | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| CTSF-RANBP3-20-AQAQ | 20 (40 μL) | 200 μL |
|
RANBP3 Gene Summary
This gene encodes a protein with a RanBD1 domain that is found in both the nucleus and cytoplasm. This protein plays a role in nuclear export as part of a heteromeric complex. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: RAN Binding Protein 3
Chromosome: CHR19: 5916151 -5978320
Locus: 19p13.3
CTSF Gene Summary
Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W. [provided by RefSeq, Jul 2008]
Gene Name: Cathepsin F
Chromosome: CHR11: 66330934 -66336047
Locus: 11q13.2
Gene Diseases
The CTSF RANBP3 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|