CTTN-PLEKHA5 Fusion FISH Probe
The CTTN-PLEKHA5 Fusion FISH Probe is used to confirm a fusion of the CTTN and PLEKHA5 genes. The fusion of the CTTN and PLEKHA5 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CTTN-PLEKHA5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-RERE | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-REOR | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-REGO | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-REGR | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-REAQ | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-ORRE | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-OROR | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-ORGO | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-ORAQ | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-GORE | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-GOOR | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-GOGO | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-GOGR | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-GOAQ | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-GRRE | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-GROR | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-GRGO | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-GRGR | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-GRAQ | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-AQRE | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-AQOR | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-AQGO | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-AQGR | 20 (40 μL) | 200 μL |
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| CTTN-PLEKHA5-20-AQAQ | 20 (40 μL) | 200 μL |
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CTTN Gene Summary
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010]
Gene Name: Cortactin
Chromosome: CHR11: 70244611 -70282690
Locus: 11q13.3
PLEKHA5 Gene Summary
The Pleckstrin Homology Domain Containing A5 (PLEKHA5) gene is located on chr12 :19282625-19529333 at 12p12.3.
Gene Name: Pleckstrin Homology Domain Containing A5
Chromosome: CHR12: 19282625 -19529333
Locus: 12p12.3
Gene Diseases
The CTTN PLEKHA5 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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