CUX2-CABP1 Fusion FISH Probe
The CUX2-CABP1 Fusion FISH Probe is used to confirm a fusion of the CUX2 and CABP1 genes. The fusion of the CUX2 and CABP1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CUX2-CABP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-RERE | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-REOR | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-REGO | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-REGR | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-REAQ | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-ORRE | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-OROR | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-ORGO | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-GORE | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-GOOR | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-GOGO | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-GOGR | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-GRRE | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-GROR | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-GRGO | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-GRGR | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-AQRE | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-AQOR | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-AQGO | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-AQGR | 20 (40 μL) | 200 μL |
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| CUX2-CABP1-20-AQAQ | 20 (40 μL) | 200 μL |
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CABP1 Gene Summary
Calcium binding proteins are an important component of calcium mediated cellular signal transduction. This gene encodes a protein that belongs to a subfamily of calcium binding proteins which share similarity to calmodulin. The protein encoded by this gene regulates the gating of voltage-gated calcium ion channels. This protein inhibits calcium-dependent inactivation and supports calcium-dependent facilitation of ion channels containing voltage-dependent L-type calcium channel subunit alpha-1C. This protein also regulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors, P/Q-type voltage-gated calcium channels, and transient receptor potential channel TRPC5. This gene is predominantly expressed in retina and brain. Alternative splicing results in multiple transcript variants encoding disinct isoforms. [provided by RefSeq, Jul 2012]
Gene Name: Calcium Binding Protein 1
Chromosome: CHR12: 121078421 -121105127
Locus: 12q24.31
CUX2 Gene Summary
This gene encodes a protein which contains three CUT domains and a homeodomain; both domains are DNA-binding motifs. A similar gene, whose gene product possesses different DNA-binding activities, is located on chromosome on chromosome 7. Two pseudogenes of this gene have been identified on chromosomes 10 and 4. [provided by RefSeq, Jan 2013]
Gene Name: Cut Like Homeobox 2
Chromosome: CHR12: 111471827 -111788358
Locus: 12q24.11-q24.12
Gene Diseases
The CUX2 CABP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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