CYP2C19-TBC1D12 Fusion FISH Probe
The CYP2C19-TBC1D12 Fusion FISH Probe is used to confirm a fusion of the CYP2C19 and TBC1D12 genes. The fusion of the CYP2C19 and TBC1D12 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CYP2C19-TBC1D12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-RERE | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-REOR | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-REGO | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-REGR | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-OROR | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-GORE | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-GROR | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| CYP2C19-TBC1D12-20-AQAQ | 20 (40 μL) | 200 μL |
|
CYP2C19 Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]
Gene Name: Cytochrome P450 Family 2 Subfamily C Member 19
Chromosome: CHR10: 96522462 -96612671
Locus: 10q23.33
TBC1D12 Gene Summary
The TBC1 Domain Family Member 12 (TBC1D12) gene is located on chr10 :96162185-96296089 at 10q23.33.
Gene Name: TBC1 Domain Family Member 12
Chromosome: CHR10: 96162185 -96296089
Locus: 10q23.33
Gene Diseases
The CYP2C19 TBC1D12 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|