CYP2C9-APOH Fusion FISH Probe
The CYP2C9-APOH Fusion FISH Probe is used to confirm a fusion of the CYP2C9 and APOH genes. The fusion of the CYP2C9 and APOH genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CYP2C9-APOH-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-RERE | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-REOR | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-REGO | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-REGR | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-REAQ | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-ORRE | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-OROR | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-ORGO | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-ORAQ | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-GORE | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-GOOR | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-GOGO | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-GOGR | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-GOAQ | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-GRRE | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-GROR | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-GRGO | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-GRGR | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-GRAQ | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-AQRE | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-AQOR | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-AQGO | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-AQGR | 20 (40 μL) | 200 μL |
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| CYP2C9-APOH-20-AQAQ | 20 (40 μL) | 200 μL |
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APOH Gene Summary
Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections. [provided by RefSeq, Jul 2008]
Gene Name: Apolipoprotein H
Chromosome: CHR17: 64208146 -64225556
Locus: 17q24.2
CYP2C9 Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]
Gene Name: Cytochrome P450 Family 2 Subfamily C Member 9
Chromosome: CHR10: 96698414 -96749148
Locus: 10q23.33
Gene Diseases
The CYP2C9 APOH Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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