DALRD3-IMPDH2 Fusion FISH Probe
The DALRD3-IMPDH2 Fusion FISH Probe is used to confirm a fusion of the DALRD3 and IMPDH2 genes. The fusion of the DALRD3 and IMPDH2 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DALRD3-IMPDH2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-RERE | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-REOR | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-REGO | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-REGR | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-REAQ | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-ORRE | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-OROR | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-ORGO | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-ORAQ | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-GORE | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-GOOR | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-GOGO | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-GOGR | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-GOAQ | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-GRRE | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-GROR | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-GRGO | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-GRGR | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-GRAQ | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-AQRE | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-AQOR | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-AQGO | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-AQGR | 20 (40 μL) | 200 μL |
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| DALRD3-IMPDH2-20-AQAQ | 20 (40 μL) | 200 μL |
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IMPDH2 Gene Summary
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
Gene Name: Inosine Monophosphate Dehydrogenase 2
Chromosome: CHR3: 49061761 -49066875
Locus: 3p21.31
DALRD3 Gene Summary
The exact function of this gene is not known. It encodes a protein with a DALR anticodon binding domain similar to that of class Ia aminoacyl tRNA synthetases. This gene is located in a cluster of genes (with a complex sense-anti-sense genome architecture) on chromosome 3, and contains two micro RNA (miRNA) precursors (mir-425 and mir-191) in one of its introns. Preferential expression of this gene (the miRNAs and other genes in the cluster) in testis suggests a role of this gene in spermatogenesis (PMID:19906709). [provided by RefSeq, Feb 2013]
Gene Name: DALR Anticodon Binding Domain Containing 3
Chromosome: CHR3: 49052434 -49058467
Locus: 3p21.31
Gene Diseases
The DALRD3 IMPDH2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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