DCAF6-HMCN1 Fusion FISH Probe
The DCAF6-HMCN1 Fusion FISH Probe is used to confirm a fusion of the DCAF6 and HMCN1 genes. The fusion of the DCAF6 and HMCN1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DCAF6-HMCN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-RERE | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-REOR | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-REGO | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-REGR | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-REAQ | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-ORRE | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-OROR | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-ORGO | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-GORE | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-GOOR | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-GOGO | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-GOGR | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-GRRE | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-GROR | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-GRGO | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-GRGR | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-AQRE | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-AQOR | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-AQGO | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-AQGR | 20 (40 μL) | 200 μL |
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| DCAF6-HMCN1-20-AQAQ | 20 (40 μL) | 200 μL |
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DCAF6 Gene Summary
The protein encoded by this gene is a ligand-dependent coactivator of nuclear receptors, including nuclear receptor subfamily 3 group C member 1 (NR3C1), glucocorticoid receptor (GR), and androgen receptor (AR). The encoded protein and DNA damage binding protein 2 (DDB2) may act as tumor promoters and tumor suppressors, respectively, by regulating the level of androgen receptor in prostate tissues. In addition, this protein can act with glucocorticoid receptor to promote human papillomavirus gene expression. [provided by RefSeq, Mar 2017]
Gene Name: DDB1 And CUL4 Associated Factor 6
Chromosome: CHR1: 167905796 -168045083
Locus: 1q24.2
HMCN1 Gene Summary
This gene encodes a large extracellular member of the immunoglobulin superfamily. A similar protein in C. elegans forms long, fine tracks at specific extracellular sites that are involved in many processes such as stabilization of the germline syncytium, anchorage of mechanosensory neurons to the epidermis, and organization of hemidesmosomes in the epidermis. Mutations in this gene may be associated with age-related macular degeneration. [provided by RefSeq, Jul 2008]
Gene Name: Hemicentin 1
Chromosome: CHR1: 185703682 -186160085
Locus: 1q25.3-q31.1
Gene Diseases
The DCAF6 HMCN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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