DCHS2-FGG Fusion FISH Probe
The DCHS2-FGG Fusion FISH Probe is used to confirm a fusion of the DCHS2 and FGG genes. The fusion of the DCHS2 and FGG genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DCHS2-FGG-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-RERE | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-REOR | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-REGO | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-REGR | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-REAQ | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-ORRE | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-OROR | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-ORGO | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-ORAQ | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-GORE | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-GOOR | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-GOGO | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-GOGR | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-GOAQ | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-GRRE | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-GROR | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-GRGO | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-GRGR | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-GRAQ | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-AQRE | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-AQOR | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-AQGO | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-AQGR | 20 (40 μL) | 200 μL |
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| DCHS2-FGG-20-AQAQ | 20 (40 μL) | 200 μL |
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FGG Gene Summary
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
Gene Name: Fibrinogen Gamma Chain
Chromosome: CHR4: 155525285 -155533902
Locus: 4q32.1
DCHS2 Gene Summary
This gene encodes a large protein that contains many cadherin domains and likely functions in cell adhesion. Genome-wide association studies suggest that this gene may be important in Alzheimer's disease, compressive strength index, and appendicular lean mass. [provided by RefSeq, May 2017]
Gene Name: Dachsous Cadherin-related 2
Chromosome: CHR4: 155243805 -155412877
Locus: 4q31.3
Gene Diseases
The DCHS2 FGG Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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