DCK-GRSF1 Fusion FISH Probe
The DCK-GRSF1 Fusion FISH Probe is used to confirm a fusion of the DCK and GRSF1 genes. The fusion of the DCK and GRSF1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DCK-GRSF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-RERE | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-REOR | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-REGO | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-REGR | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-REAQ | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-ORRE | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-OROR | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-ORGO | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-GORE | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-GOOR | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-GOGO | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-GOGR | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-GRRE | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-GROR | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-GRGO | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-GRGR | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-AQRE | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-AQOR | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-AQGO | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-AQGR | 20 (40 μL) | 200 μL |
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| DCK-GRSF1-20-AQAQ | 20 (40 μL) | 200 μL |
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DCK Gene Summary
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008]
Gene Name: Deoxycytidine Kinase
Chromosome: CHR4: 71859264 -71896629
Locus: 4q13.3
GRSF1 Gene Summary
The protein encoded by this gene is a cellular protein that binds RNAs containing the G-rich element. The protein is localized in the cytoplasm, and has been shown to stimulate translation of viral mRNAs in vitro. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: G-rich RNA Sequence Binding Factor 1
Chromosome: CHR4: 71681498 -71705627
Locus: 4q13.3
Gene Diseases
The DCK GRSF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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