DCP2-IL17B Fusion FISH Probe
The DCP2-IL17B Fusion FISH Probe is used to confirm a fusion of the DCP2 and IL17B genes. The fusion of the DCP2 and IL17B genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DCP2-IL17B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-RERE | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-REOR | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-REGO | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-REGR | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-OROR | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-GORE | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-GROR | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| DCP2-IL17B-20-AQAQ | 20 (40 μL) | 200 μL |
|
IL17B Gene Summary
The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. Alternative splicing results in multiple splice variants. [provided by RefSeq, Dec 2015]
Gene Name: Interleukin 17B
Chromosome: CHR5: 148753829 -148758838
Locus: 5q32
DCP2 Gene Summary
The protein encoded by this gene is a key component of an mRNA-decapping complex required for degradation of mRNAs, both in normal mRNA turnover, and in nonsense-mediated mRNA decay (NMD). It removes the 7-methyl guanine cap structure from mRNA, prior to its degradation from the 5' end. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]
Gene Name: Decapping MRNA 2
Chromosome: CHR5: 112312406 -112357892
Locus: 5q22.2
Gene Diseases
The DCP2 IL17B Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|