DCUN1D4-USP46 Fusion FISH Probe
The DCUN1D4-USP46 Fusion FISH Probe is used to confirm a fusion of the DCUN1D4 and USP46 genes. The fusion of the DCUN1D4 and USP46 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DCUN1D4-USP46-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-RERE | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-REOR | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-REGO | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-REGR | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-REAQ | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-ORRE | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-OROR | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-ORGO | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-ORAQ | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-GORE | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-GOOR | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-GOGO | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-GOGR | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-GOAQ | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-GRRE | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-GROR | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-GRGO | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-GRGR | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-GRAQ | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-AQRE | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-AQOR | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-AQGO | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-AQGR | 20 (40 μL) | 200 μL |
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| DCUN1D4-USP46-20-AQAQ | 20 (40 μL) | 200 μL |
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DCUN1D4 Gene Summary
The Defective In Cullin Neddylation 1 Domain Containing 4 (DCUN1D4) gene is located on chr4 :52709275-52783003 at 4q12.
Gene Name: Defective In Cullin Neddylation 1 Domain Containing 4
Chromosome: CHR4: 52709275 -52783003
Locus: 4q12
USP46 Gene Summary
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Jun 2009]
Gene Name: Ubiquitin Specific Peptidase 46
Chromosome: CHR4: 53457126 -53525502
Locus: 4q12
Gene Diseases
The DCUN1D4 USP46 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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