DCX-PASD1 Fusion FISH Probe
The DCX-PASD1 Fusion FISH Probe is used to confirm a fusion of the DCX and PASD1 genes. The fusion of the DCX and PASD1 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DCX-PASD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| DCX-PASD1-20-AQAQ | 20 (40 μL) | 200 μL |
|
DCX Gene Summary
This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, cognitive disability, subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain" syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]
Gene Name: Doublecortin
Chromosome: CHRX: 110537006 -110655460
Locus: Xq23
PASD1 Gene Summary
This gene encodes a protein that is thought to function as a transcription factor. The protein is a cancer-associated antigen that can stimulate autologous T-cell responses, and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies, including diffuse large B-cell lymphoma. [provided by RefSeq, May 2010]
Gene Name: PAS Domain Containing Repressor 1
Chromosome: CHRX: 150732006 -150845211
Locus: Xq28
Gene Diseases
The DCX PASD1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|