DDA1-MYO9B Fusion FISH Probe
The DDA1-MYO9B Fusion FISH Probe is used to confirm a fusion of the DDA1 and MYO9B genes. The fusion of the DDA1 and MYO9B genes has been associated with Uterine Corpus Endometrial Carcinoma, and Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DDA1-MYO9B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-RERE | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-REOR | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-REGO | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-REGR | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-REAQ | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-ORRE | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-OROR | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-ORGO | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-ORAQ | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-GORE | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-GOOR | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-GOGO | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-GOGR | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-GOAQ | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-GRRE | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-GROR | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-GRGO | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-GRGR | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-GRAQ | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-AQRE | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-AQOR | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-AQGO | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-AQGR | 20 (40 μL) | 200 μL |
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| DDA1-MYO9B-20-AQAQ | 20 (40 μL) | 200 μL |
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MYO9B Gene Summary
This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Name: Myosin IXB
Chromosome: CHR19: 17186590 -17324104
Locus: 19p13.11
DDA1 Gene Summary
The DET1 And DDB1 Associated 1 (DDA1) gene is located on chr19 :17420336-17434106 at 19p13.11.
Gene Name: DET1 And DDB1 Associated 1
Chromosome: CHR19: 17420336 -17434106
Locus: 19p13.11
Gene Diseases
The DDA1 MYO9B Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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