DDX17-ARFGEF2 Fusion FISH Probe
The DDX17-ARFGEF2 Fusion FISH Probe is used to confirm a fusion of the DDX17 and ARFGEF2 genes. The fusion of the DDX17 and ARFGEF2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DDX17-ARFGEF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-RERE | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-REOR | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-REGO | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-REGR | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-REAQ | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-ORRE | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-OROR | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-ORGO | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-GORE | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-GOOR | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-GOGO | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-GOGR | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-GRRE | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-GROR | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-GRGO | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-GRGR | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-AQRE | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-AQOR | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-AQGO | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-AQGR | 20 (40 μL) | 200 μL |
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| DDX17-ARFGEF2-20-AQAQ | 20 (40 μL) | 200 μL |
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DDX17 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon. [provided by RefSeq, Apr 2011]
Gene Name: DEAD-box Helicase 17
Chromosome: CHR22: 38879442 -38902345
Locus: 22q13.1
ARFGEF2 Gene Summary
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
Gene Name: ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 2
Chromosome: CHR20: 47538274 -47653230
Locus: 20q13.13
Gene Diseases
The DDX17 ARFGEF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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