DDX17-EIF2AK2 Fusion FISH Probe
The DDX17-EIF2AK2 Fusion FISH Probe is used to confirm a fusion of the DDX17 and EIF2AK2 genes. The fusion of the DDX17 and EIF2AK2 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DDX17-EIF2AK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-RERE | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-REOR | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-REGO | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-REGR | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-REAQ | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-ORRE | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-OROR | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-ORGO | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-GORE | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-GOOR | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-GOGO | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-GOGR | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-GRRE | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-GROR | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-GRGO | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-GRGR | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-AQRE | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-AQOR | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-AQGO | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-AQGR | 20 (40 μL) | 200 μL |
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| DDX17-EIF2AK2-20-AQAQ | 20 (40 μL) | 200 μL |
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EIF2AK2 Gene Summary
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2
Chromosome: CHR2: 37333698 -37384190
Locus: 2p22.2
DDX17 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon. [provided by RefSeq, Apr 2011]
Gene Name: DEAD-box Helicase 17
Chromosome: CHR22: 38879442 -38902345
Locus: 22q13.1
Gene Diseases
The DDX17 EIF2AK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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