DDX42-RPS6KB1 Fusion FISH Probe
The DDX42-RPS6KB1 Fusion FISH Probe is used to confirm a fusion of the DDX42 and RPS6KB1 genes. The fusion of the DDX42 and RPS6KB1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DDX42-RPS6KB1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-RERE | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-REOR | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-REGO | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-REGR | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-REAQ | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-ORRE | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-OROR | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-ORGO | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-ORAQ | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-GORE | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-GOOR | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-GOGO | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-GOGR | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-GOAQ | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-GRRE | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-GROR | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-GRGO | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-GRGR | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-GRAQ | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-AQRE | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-AQOR | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-AQGO | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-AQGR | 20 (40 μL) | 200 μL |
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| DDX42-RPS6KB1-20-AQAQ | 20 (40 μL) | 200 μL |
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RPS6KB1 Gene Summary
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]
Gene Name: Ribosomal Protein S6 Kinase B1
Chromosome: CHR17: 57970442 -58027786
Locus: 17q23.1
DDX42 Gene Summary
This gene encodes a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: DEAD-box Helicase 42
Chromosome: CHR17: 61851566 -61896677
Locus: 17q23.3
Gene Diseases
The DDX42 RPS6KB1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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