DEK-KIF25 Fusion FISH Probe
The DEK-KIF25 Fusion FISH Probe is used to confirm a fusion of the DEK and KIF25 genes. The fusion of the DEK and KIF25 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DEK-KIF25-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-RERE | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-REOR | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-REGO | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-REGR | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-REAQ | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-ORRE | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-OROR | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-ORGO | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-ORAQ | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-GORE | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-GOOR | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-GOGO | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-GOGR | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-GOAQ | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-GRRE | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-GROR | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-GRGO | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-GRGR | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-GRAQ | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-AQRE | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-AQOR | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-AQGO | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-AQGR | 20 (40 μL) | 200 μL |
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| DEK-KIF25-20-AQAQ | 20 (40 μL) | 200 μL |
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KIF25 Gene Summary
The protein encoded by this gene is a member of the kinesin-like protein family. Protein family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. However, the particular function of this gene product has not yet been determined. Two alternatively spliced transcript variants which encode products have been described. Other splice variants have been found that lack exon 2 and the initiation codon for translation. [provided by RefSeq, Jul 2008]
Gene Name: Kinesin Family Member 25
Chromosome: CHR6: 168418552 -168445769
Locus: 6q27
DEK Gene Summary
This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Gene Name: DEK Proto-oncogene
Chromosome: CHR6: 18224399 -18264799
Locus: 6p22.3
Gene Diseases
The DEK KIF25 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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