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DENND1B-RRP15 Fusion FISH Probe

The DENND1B-RRP15 Fusion FISH Probe is used to confirm a fusion of the DENND1B and RRP15 genes. The fusion of the DENND1B and RRP15 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DENND1B-RRP15-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
DENND1B-RRP15-20-RERE 20 (40 μL) 200 μL
DENND1B-RRP15-20-REOR 20 (40 μL) 200 μL
DENND1B-RRP15-20-REGO 20 (40 μL) 200 μL
DENND1B-RRP15-20-REGR 20 (40 μL) 200 μL
DENND1B-RRP15-20-REAQ 20 (40 μL) 200 μL
DENND1B-RRP15-20-ORRE 20 (40 μL) 200 μL
DENND1B-RRP15-20-OROR 20 (40 μL) 200 μL
DENND1B-RRP15-20-ORGO 20 (40 μL) 200 μL
DENND1B-RRP15-20-ORAQ 20 (40 μL) 200 μL
DENND1B-RRP15-20-GORE 20 (40 μL) 200 μL
DENND1B-RRP15-20-GOOR 20 (40 μL) 200 μL
DENND1B-RRP15-20-GOGO 20 (40 μL) 200 μL
DENND1B-RRP15-20-GOGR 20 (40 μL) 200 μL
DENND1B-RRP15-20-GOAQ 20 (40 μL) 200 μL
DENND1B-RRP15-20-GRRE 20 (40 μL) 200 μL
DENND1B-RRP15-20-GROR 20 (40 μL) 200 μL
DENND1B-RRP15-20-GRGO 20 (40 μL) 200 μL
DENND1B-RRP15-20-GRGR 20 (40 μL) 200 μL
DENND1B-RRP15-20-GRAQ 20 (40 μL) 200 μL
DENND1B-RRP15-20-AQRE 20 (40 μL) 200 μL
DENND1B-RRP15-20-AQOR 20 (40 μL) 200 μL
DENND1B-RRP15-20-AQGO 20 (40 μL) 200 μL
DENND1B-RRP15-20-AQGR 20 (40 μL) 200 μL
DENND1B-RRP15-20-AQAQ 20 (40 μL) 200 μL

RRP15 Gene Summary

This gene encodes a protein that co-purifies with human nucleoli. A similar protein in budding yeast is a component of pre-60S ribosomal particles, and is required for the early maturation steps of the 60S subunit. [provided by RefSeq, Jul 2008]

Gene Name: Ribosomal RNA Processing 15 Homolog

Chromosome: CHR1: 218458628 -218511325

Locus: 1q41

DENND1B Gene Summary

Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010]

Gene Name: DENN Domain Containing 1B

Chromosome: CHR1: 197473878 -197744623

Locus: 1q31.3

Gene Diseases

The DENND1B RRP15 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.